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Local anaesthesia decreases nerve growth factor induced masseter hyperalgesia

Yuri M Costa1,2,3, Fernando G Exposto4,5, Eduardo E Castrillon4,5

  • 1Department of Biosciences, Piracicaba Dental School, University of Campinas, Av. Limeira, 901, Piracicaba, CEP 13414-903, Brazil. yuricosta@fop.unicamp.br.

Scientific Reports
|September 23, 2020
PubMed
Summary

Local anesthesia reduced nerve growth factor (NGF)-induced jaw pain and mechanical sensitivity in the masseter muscle. This suggests peripheral mechanisms contribute to persistent musculoskeletal pain.

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