Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

Role of Cerebellum and Prefrontal Cortex in Memory

Role of Cerebellum and Prefrontal Cortex in Memory

The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Exploring brain-glioma interaction: Effect of neuroligin-3 expression on neurocognitive functioning is independent from epilepsy.

Neuro-oncology advances·2026

Same author

Validation of the ED-15-NL, a Brief Session-by-Session Questionnaire to Measure Changes in Eating Disorder Cognitions and Behaviors.

The International journal of eating disorders·2026

Same author

Negative impact of hippocampal radiotherapy dose on memory function in patients with brain metastases.

Neuro-oncology practice·2026

Same author

Understanding the unmet needs of patients with brain metastases referred for stereotactic radiotherapy and their caregivers: A prospective cohort study.

Neuro-oncology practice·2026

Same author

Temporal responses in sensorimotor cortex during hand movements.

PloS one·2026

Same author

Implanted brain-computer interface functionality during nighttime in late-stage amyotrophic lateral sclerosis.

Scientific reports·2026

Same journal

Turbulent flow in a vortex separator with a directed pipe inlet.

Scientific reports·2026

Same journal

Systematic characteristic evaluation of clay-based cementitious material derived from calcium carbide residue and waste tile powder.

Scientific reports·2026

Same journal

Retraction Note: Improvement of a rapid diagnostic application of monoclonal antibodies against avian influenza H7 subtype virus using Europium nanoparticles.

Scientific reports·2026

Same journal

Applying large language models to spam detection in the Kazakh low-resource language setting.

Scientific reports·2026

Same journal

An open-source 3D printing system enabling in-situ freeze-thaw processing of hydrogels.

Scientific reports·2026

Same journal

An enhanced EfficientNet framework for automated waste classification using cosine annealing and label smoothing.

Scientific reports·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Dec 8, 2025

Brain-Computer Interface-controlled Upper Limb Robotic System for Enhancing Daily Activities in Stroke Patients

Brain-Computer Interface-controlled Upper Limb Robotic System for Enhancing Daily Activities in Stroke Patients

Published on: April 18, 2025

Dorsolateral prefrontal cortex-based control with an implanted brain-computer interface.

Sacha Leinders¹, Mariska J Vansteensel¹, Mariana P Branco¹

¹UMC Utrecht Brain Center, Department of Neurology and Neurosurgery, University Medical Center, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.

Scientific Reports

|September 23, 2020

Summary

This summary is machine-generated.

Brain-computer interface control using the dorsolateral prefrontal cortex is feasible for individuals with locked-in syndrome. This neuroprosthesis shows promise for restoring communication in severe motor impairment.

More Related Videos

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface

Published on: May 8, 2021

Assessment and Communication for People with Disorders of Consciousness

Assessment and Communication for People with Disorders of Consciousness

Published on: August 1, 2017

Related Experiment Videos

Last Updated: Dec 8, 2025

Brain-Computer Interface-controlled Upper Limb Robotic System for Enhancing Daily Activities in Stroke Patients

Brain-Computer Interface-controlled Upper Limb Robotic System for Enhancing Daily Activities in Stroke Patients

Published on: April 18, 2025

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface

Published on: May 8, 2021

Assessment and Communication for People with Disorders of Consciousness

Assessment and Communication for People with Disorders of Consciousness

Published on: August 1, 2017

Area of Science:

Neuroscience
Biomedical Engineering
Rehabilitation Medicine

Background:

Severe motor impairments, such as locked-in syndrome, severely limit communication.
Brain-computer interfaces (BCIs) offer a potential avenue for restoring communication.
The dorsolateral prefrontal cortex (DLPFC) is explored as a novel signal source for BCIs.

Observation:

Two individuals with locked-in syndrome received chronic subdural implants over the DLPFC.
The Utrecht NeuroProsthesis system was used to monitor DLPFC activity.
Participants consistently activated the DLPFC during a counting-backwards task over extended periods (47 and 22 months).

Findings:

DLPFC activation was reliably detected in both participants.
Participants successfully utilized DLPFC signals to control a one-dimensional cursor.
High average accuracy scores (78% ± 9% and 71% ± 11%) were achieved, significantly above chance (50%).

Implications:

DLPFC-based BCI control is a feasible strategy for individuals with locked-in syndrome.
This approach may provide an alternative for patients unable to use traditional sensorimotor BCIs.
Further research into DLPFC-based BCIs could significantly advance assistive communication technologies.