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Acute myocardial infarction, as a rare manifestation in granulomatosis with polyangiitis

Lucía V Maya-Piña1, Rosa E Barbosa-Cobos1, Gustavo E Lugo-Zamudio2

  • 1Servicio de Reumatología, Hospital Juárez de México. Ciudad de México, México.

Cirugia Y Cirujanos
|September 23, 2020
PubMed

Insights

Granulomatosis with polyangiitis, a rare condition, can cause heart problems like myocardial infarction. Early recognition of cardiac symptoms in GPA is crucial for patient prognosis.

Area of Science:

  • Rheumatology
  • Cardiology
  • Internal Medicine

Background:

  • Granulomatosis with polyangiitis (GPA) is a small vessel vasculitis associated with anti-neutrophil cytoplasmic antibodies (ANCA).
  • Cardiac manifestations in GPA are uncommon but can include pericarditis, myocarditis, coronary arteritis, and valvular disease.

Observation:

  • A 49-year-old male with a recent GPA diagnosis presented with acute myocardial infarction.
  • The myocardial infarction was attributed to active GPA disease processes.

Findings:

  • This case highlights a rare but serious cardiac complication of GPA.
  • Cardiovascular manifestations in GPA are significant indicators of a poor prognosis.

Implications:

  • Increased awareness of cardiac involvement in GPA is necessary for timely diagnosis and management.
  • Prognosis in GPA patients with cardiac involvement may be poorer, necessitating closer monitoring.
  • Further research into the mechanisms and management of cardiac GPA is warranted.

Keywords:
Arteritis coronariaCardiac diseaseCardiac involvementCardiac manifestationsCoronary arteritisEnfermedad cardíacaGranulomatosis con poliangeítisGranulomatosis with polyangiitisInvolucro cardíacoManifestaciones cardíacas

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