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Echocardiography in Confirmed and Highly Suspected Symptomatic COVID-19 Patients and Its Impact on Treatment Change
Nadia Benyounes1, Clélie Van Der Vynckt1, Séverine Tibi2
1Cardiology Unit, Rothschild Foundation Hospital, Paris, France.
Insights
Echocardiography can guide treatment changes in 16% of COVID-19 patients, particularly those with elevated cardiac biomarkers. This cardiac imaging tool aids in managing cardiovascular complications in selected coronavirus disease patients.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Imaging
Background:
- COVID-19 significantly impacts the cardiovascular system, worsening prognosis for patients with pre-existing heart conditions.
- The virus can cause severe cardiovascular complications, including myocardial injury in up to 20% of critically ill patients.
Purpose of the Study:
- To investigate the impact of echocardiography on the clinical management of patients diagnosed with COVID-19.
- To identify predictors of treatment modification based on echocardiographic findings in COVID-19 patients.
Main Methods:
- A single-center study included consecutive inpatients with confirmed or suspected COVID-19.
- Echocardiographic data, clinical characteristics, and biological markers were collected and analyzed.
- Treatment changes induced by echocardiography were recorded and compared between patient groups.
Main Results:
- Echocardiography led to treatment changes in 16% of the 42 evaluated COVID-19 patients.
- Elevated D-dimer and Troponin levels, higher systolic pulmonary arterial pressure, and cardiac thrombi were associated with treatment modifications.
- Clinical data alone did not predict treatment changes.
Conclusions:
- Echocardiography is a valuable tool for managing selected COVID-19 patients, especially those with elevated cardiac biomarkers.
- The findings suggest echocardiography can optimize treatment strategies for COVID-19 patients with cardiovascular involvement.
Background:
COVID-19 interacts at multiple levels with the cardiovascular system. The prognosis of COVID-19 infection is known to be worse for patients with underlying cardiovascular diseases. Furthermore, the virus is responsible for many cardiovascular complications. Myocardial injury may affect up to 20% of the critically ill patients. However, echocardiography's impact on the management of patients affected by COVID-19 remains unknown.
Objectives:
To explore echocardiography's impact on the management of COVID-19 patients.
Methods:
This study was conducted from March 24th to April 14th, 2020, in a single center at Adolphe de Rothschild Foundation Hospital, Paris, France. All consecutive inpatients with laboratory and/or CT COVID-19 diagnosis were included in this study. Patients' characteristics (clinical, biological, and imaging) and treatment change induced by echocardiography were collected and analyzed. Patients with and without treatment change induced by echocardiography were compared.
Results:
A total of 56 echocardiographies in 42 patients with highly suspected or confirmed COVID-19 were included in the final analyses. The median age was 66 (IQR 60.5-74). Echocardiography induced a treatment change in 9 cases (16%). The analyzed clinical data were not associated with any treatment change induced by echocardiography. D-dimer and Troponin levels were the only biological predictors of the induced treatment change. On echocardiography, higher systolic pulmonary arterial pressure and documented cardiac thrombi were associated with treatment changes in these patients.
Conclusions:
Echocardiography may be useful for the management of selected COVID-19 patients, especially those with elevated D-Dimer and Troponin levels, in up to 16% of patients.
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