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Three Case Reports of Intravenous Leiomyomatosis with Intracardiac Extensions

Yundan Deng1, Bing Song1

  • 1Department of Cardiovascular Surgery, Lanzhou University First Affiliated Hospital, Lanzhou, China.

The Thoracic and Cardiovascular Surgeon Reports
|September 23, 2020
PubMed

Insights

Intravenous leiomyomatosis, a rare condition, can have malignant behavior despite benign histology. Complete surgical removal of intracardiac extensions is the gold standard treatment, with a low recurrence rate observed.

Area of Science:

  • Cardiovascular Surgery
  • Gynecologic Oncology
  • Pathology

Background:

  • Intravenous leiomyomatosis (IVL) is a rare neoplastic disease characterized by benign histological features but potentially malignant behavior.
  • Intracardiac extension of IVL can lead to severe complications, including congestive heart failure and sudden death.

Observation:

  • Retrospective analysis of three patients treated between 2017 and 2018.
  • All patients underwent complete surgical resection of intravenous tumors extending into the right heart system.
  • No perioperative complications or mortality were observed during the procedures.

Findings:

  • Complete surgical resection was achieved in all cases of IVL with intracardiac extension.
  • A single instance of tumor recurrence was noted during the follow-up period.
  • Surgical intervention demonstrated a favorable outcome in managing this rare condition.

Implications:

  • Complete and successful surgical resection is confirmed as the gold standard treatment for IVL with intracardiac extension.
  • This approach offers a viable strategy for managing a potentially life-threatening condition.
  • Further research into long-term outcomes and adjuvant therapies may be warranted.

Keywords:
cardiovascular surgeryheart diseasetumor

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