18F-FBPA PET in Sarcoidosis: Comparison to Inflammation-Related Uptake on FDG PET
Tadashi Watabe, Hiroaki Shimamoto1, Sadahiro Naka2
1Department of Oral and Maxillofacial Radiology, Graduate School of Dentistry, Osaka University.
Abstract:
A 68-year-old man with sarcoidosis showed high F-FDG uptake in the mediastinal and hilar lymph nodes on F-FDG PET, suggesting active inflammation. F-fluoro-boronophenylalanine (FBPA) PET showed no significant uptake in the mediastinal and hilar lymph nodes, suggesting its cancer specificity as a substrate of L-type amino acid transporter 1. F-fluoro-boronophenylalanine PET can be used for precise evaluation in oncology when the differentiation between inflammation and metastasis is inconclusive on F-FDG PET.
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