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Updated: Dec 8, 2025

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery
Published on: January 15, 2018
Functionalized Gold Nanoparticles: Synthesis, Properties and Biomedical Applications.
Jianuo Fan1, Yuqing Cheng1, Mengtao Sun1
1School of Mathematics and Physics, Beijing Advanced Innovation Center for Materials Genome Engineering, Beijing Key Laboratory for Magneto-Photoelectrical Composite and Interface Science, University of Science and Technology Beijing, Beijing, 100083, P. R. China.
Functionalized gold nanoparticles offer vast potential in medicine and diagnostics due to their unique optical and plasmon properties. This review details their synthesis, characteristics, and recent biological applications.
Area of Science:
- Nanotechnology
- Materials Science
- Biomedical Engineering
Background:
- Gold nanoparticles (AuNPs) possess unique optical and plasmonic properties.
- Functionalized AuNPs are integral to drug delivery, biosensing, and clinical treatments.
- The rapid advancement of functionalized AuNPs necessitates a review of current research.
Purpose of the Study:
- To review recent advancements in the synthesis of functionalized gold nanoparticles.
- To summarize the key characteristics, including catalytic, antioxidant, and chiral optical properties.
- To consolidate the latest research progress in the biological applications of functionalized AuNPs.
Main Methods:
- Review of established and improved synthetic methodologies for functionalized AuNPs.
- Detailed summary of characteristic properties: catalytic activity, oxidation resistance, and chirality.
- Compilation and analysis of recent biological applications and research findings.
Main Results:
- Improvements in common synthetic methods for functionalized AuNPs are highlighted.
- Comprehensive overview of AuNPs' catalytic, oxidation resistance, and chirality optical properties.
- Significant progress in the biological applications of functionalized AuNPs is presented.
Conclusions:
- Functionalized gold nanoparticles are versatile nanomaterials with expanding applications.
- Understanding synthesis and properties is crucial for optimizing biological utility.
- This review provides a consolidated resource for researchers in the field.

