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Endovascular therapy for floating thrombus in the inferior vena cava
Zhi-Wen Zhang1, Xue-Ming Chen1, Ren-Ming Zhu1
1Department of Vascular Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Insights
Floating thrombus in the inferior vena cava (IVC) often arises from branch vein thrombosis and can lead to pulmonary embolism. Treatment with anticoagulation and debulking, protected by IVC filters, yields good outcomes.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Cardiology
Background:
- Floating thrombus in the inferior vena cava (IVC) presents a significant risk for pulmonary embolism.
- Understanding the clinical characteristics and predisposing factors is crucial for effective management.
Purpose of the Study:
- To summarize the clinical characteristics of patients with floating thrombus in the IVC.
- To review the diagnostic and therapeutic approaches for IVC floating thrombus.
Main Methods:
- A retrospective review of four patients with IVC floating thrombus treated between January 2014 and June 2019.
- Analysis of diagnostic methods (inferior venacavography, contrast-enhanced CT), predisposing conditions, and intracavitary therapies.
Main Results:
- Pulmonary embolism was present in three patients.
- Predisposing factors included deep venous thrombosis, double IVC, iliac vein compression syndrome, and renal phlebothrombosis.
- All patients received temporary IVC filters, anticoagulation, debulking, and thrombolysis with satisfactory results.
Conclusions:
- Floating IVC thrombus often originates from branch vein thrombosis and carries a high risk of pulmonary embolism.
- Combined therapy of anticoagulation and debulking, with IVC filter protection, is effective in managing IVC floating thrombus.
Objective:
We aimed to summarize the clinical characteristics of floating thrombus in the inferior vena cava (IVC).
Methods:
From January 2014 to June 2019, four patients with floating thrombus in the IVC were admitted to our hospital and underwent intracavitary therapy. Diagnosis, therapy, and clinical characteristics of floating thrombus were summarized.
Results:
Three patients presented with pulmonary embolism. Three of the patients had a floating thrombus discovered by inferior venacavography and one was found by contrast-enhanced computed tomography. Two patients had deep venous thrombosis in the lower extremities. One patient had a double IVC, one had left iliac vein compression syndrome, and one had right renal phlebothrombosis. The four patients underwent implantation of a temporary IVC filter and were treated with anti-coagulation, debulking, and thrombolysis. All four patients achieved satisfactory results.
Conclusions:
Floating thrombus in the IVC is often caused by spread of branch vein thrombosis, and is more likely to lead to pulmonary embolism. Anti-coagulant therapy and debulking under the protection of filters can achieve satisfactory clinical results.
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