Related Experiment Video
Updated: Dec 7, 2025

A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position
Published on: April 1, 2022
Ross Procedures in Children With Previous Aortic Valve Surgery
Edward Buratto1, Fraser R O Wallace2, Tyson A Fricke1
1Department of Cardiac Surgery, Royal Children's Hospital, Melbourne, Victoria, Australia; Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia; Heart Research Group, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
The secondary Ross procedure offers better long-term survival and fewer reoperations compared to the primary Ross procedure in children. This suggests a delayed Ross procedure after initial aortic valve repair may be more beneficial.
Area of Science:
- Pediatric cardiac surgery
- Aortic valve replacement
- Autograft procedures
Background:
- The Ross procedure is a surgical technique for aortic valve replacement in children.
- It can be performed as a primary operation or a secondary procedure following prior aortic valve surgery.
Purpose of the Study:
- To compare the outcomes of primary versus secondary Ross procedures in pediatric patients.
- To evaluate long-term survival and freedom from reoperation between the two groups.
Main Methods:
- Retrospective analysis of 140 pediatric patients undergoing the Ross procedure between 1995 and 2018.
- Comparison of outcomes between primary and secondary Ross procedure groups.
- Propensity score matching was used to control for baseline characteristics and risk factors.
Main Results:
- In the matched cohort, 10-year survival was higher in the secondary Ross group (96.8%) compared to the primary Ross group (90.0%) (p=0.04).
- Freedom from autograft reoperation at 10 years was significantly better in the secondary Ross group (97.0%) versus the primary Ross group (82%) (p=0.03).
- No significant differences in survival or reoperation were noted in the unmatched cohort.
Conclusions:
- The secondary Ross procedure demonstrates superior long-term survival and freedom from autograft reoperation compared to the primary Ross procedure.
- Considering aortic valve repair followed by a delayed Ross procedure may enhance long-term outcomes.
More Related Videos
Related Concept Videos
Aortic Regurgitation III: Medical Management
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aneurysm IV: Nursing Management
Aortic Regurgitation I: Introduction
Aneurysm III: Interprofessional Care
Aortic Regurgitation IV: Nursing Management

