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Updated: Dec 7, 2025

A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo
Published on: August 11, 2018
Can radiation-recall predict long lasting response to immune checkpoint inhibitors?
Eric Deutsch1, Benjamin Besse2, Jérôme Le Pavec3
1Department of Radiation Oncology, Institut d'Oncologie Thoracique (IOT), Gustave Roussy, France; Université Paris-Saclay, Le Kremlin-Bicêtre, France; INSERM U1030, Molecular Radiotherapy, Gustave Roussy, Université Paris-Saclay, Villejuif, France.
Abstract:
RR secondary to ICI (nivolumab in all patients) were observed in the lung (n = 1) or skin (n = 3). All patients had a long-term response to ICI and are currently alive with no active disease (Median FU from ICI discontinuation: 30 months). RR could reflect a beneficial immune activation and constitute a predictive clinical biomarker of ICI long-term efficacy.
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