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Published on: August 8, 2022
Morphological Characteristics of the Osteoplastic Potential of Synthetic CaSiO3/HAp Powder Biocomposite
Vladimir Apanasevich1, Evgeniy Papynov2,3, Nataliay Plehova1
1Central Research Laboratory, Institute of Surgery, Pacific State Medical University, 2, Ostryakov Aven., Vladivostok 690990, Russia.
Abstract:
The study describes the influence of synthetic CaSiO3/HAp powder biocomposite on the process of regeneration in osseous tissue in the alveolar ridges in terms of the morphological characteristics of the osteoplastic potential. The authors investigated the osteoinduction and osteoconduction "in vivo" processes during bone tissue regeneration in the mandible defect area of an experimental animal (rabbit). The possibility of angiogenesis in the graft as an adaptation factor was studied in the process of bone tissue regeneration. The results of the histological study that included the qualitative parameters of bone tissue regeneration, the morphometric parameters (microarchitectonics) of the bone, the parameters of osteosynthesis (thickness of the osteoid plates), and resorption (volume density of the eroded surface) were presented. The results allowed the authors to characterize the possibility of the practical adaptation for synthetic powder biocomposite as an osteoplastic graft for the rehabilitation of osseous defects in dentistry.

