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Related Experiment Video

Updated: Dec 7, 2025

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology

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MR Target Sign in Cerebral Aspergillosis.

Pasquale F Finelli¹

¹Department of Neurology, Hartford Hospital and University of Connecticut School of Medicine, Hartford, CT, USA.

The Neurohospitalist

|September 28, 2020

Summary

This summary is machine-generated.

Magnetic resonance (MR) imaging is key for brain infections, but often lacks specific signs. We highlight the MR apparent diffusion coefficient/T2-weighted target sign for diagnosing cerebral aspergillosis, aiding early treatment.

Keywords:

MR target sign cerebral aspergillosis idiopathic CD4 lymphocytopenia

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Last Updated: Dec 7, 2025

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology

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Published on: March 22, 2012

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Published on: September 18, 2021

Area of Science:

Neuroimaging
Infectious Diseases
Radiology

Background:

Magnetic resonance (MR) is crucial for diagnosing infectious brain diseases.
However, MR findings in these conditions are frequently nonspecific.
Early diagnosis is vital due to high mortality rates.

Purpose of the Study:

To highlight a specific diagnostic feature on MR imaging.
To improve the diagnosis of cerebral aspergillosis.
To facilitate timely and effective treatment.

Main Methods:

Review of MR imaging findings in cerebral aspergillosis.
Identification and characterization of the apparent diffusion coefficient/T2-weighted target sign.
Correlation of imaging findings with clinical diagnosis.

Main Results:

The apparent diffusion coefficient/T2-weighted target sign is a distinctive MR finding.
This sign aids in differentiating cerebral aspergillosis from other infectious etiologies.
Specific imaging features can significantly improve diagnostic accuracy.

Conclusions:

The MR apparent diffusion coefficient/T2-weighted target sign is a valuable diagnostic tool.
Its recognition can lead to earlier diagnosis and treatment of cerebral aspergillosis.
This finding has significant implications for patient management and outcomes.