MR Target Sign in Cerebral Aspergillosis

Pasquale F Finelli1

  • 1Department of Neurology, Hartford Hospital and University of Connecticut School of Medicine, Hartford, CT, USA.

The Neurohospitalist
|September 28, 2020
PubMed

Insights

Magnetic resonance (MR) imaging is key for brain infections, but often lacks specific signs. We highlight the MR apparent diffusion coefficient/T2-weighted target sign for diagnosing cerebral aspergillosis, aiding early treatment.

Area of Science:

  • Neuroimaging
  • Infectious Diseases
  • Radiology

Background:

  • Magnetic resonance (MR) is crucial for diagnosing infectious brain diseases.
  • However, MR findings in these conditions are frequently nonspecific.
  • Early diagnosis is vital due to high mortality rates.

Purpose of the Study:

  • To highlight a specific diagnostic feature on MR imaging.
  • To improve the diagnosis of cerebral aspergillosis.
  • To facilitate timely and effective treatment.

Main Methods:

  • Review of MR imaging findings in cerebral aspergillosis.
  • Identification and characterization of the apparent diffusion coefficient/T2-weighted target sign.
  • Correlation of imaging findings with clinical diagnosis.

Main Results:

  • The apparent diffusion coefficient/T2-weighted target sign is a distinctive MR finding.
  • This sign aids in differentiating cerebral aspergillosis from other infectious etiologies.
  • Specific imaging features can significantly improve diagnostic accuracy.

Conclusions:

  • The MR apparent diffusion coefficient/T2-weighted target sign is a valuable diagnostic tool.
  • Its recognition can lead to earlier diagnosis and treatment of cerebral aspergillosis.
  • This finding has significant implications for patient management and outcomes.

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