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Related Experiment Video

Updated: Sep 20, 2025

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Published on: September 25, 2019

"Innumerable" lesion burden on brain MRI ‒ a diagnostic approach.

Pasquale F Finelli^1,2

¹Department of Neurology, 156165 Hartford Hospital and University of Connecticut School of Medicine , Hartford, CT, USA.

Diagnosis (Berlin, Germany)

|May 26, 2025

Summary

This summary is machine-generated.

Innumerable brain lesions on MRI are rare but can be diagnosed. Identifying risk factors and specific MRI sequences aids in creating a diagnostic algorithm for these challenging cases.

Keywords:

MR imaging diagnostic algorithm innumerable lesions risk factors

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Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Published on: November 20, 2015

Area of Science:

Neuroradiology
Neuroimaging
Diagnostic Radiology

Background:

The term "innumerable" on brain MRI signifies a rare and diagnostically challenging lesion burden.
Systematic studies on brain MR imaging findings described as "innumerable" are lacking.

Purpose of the Study:

To determine risk factors associated with innumerable brain lesions on MRI.
To identify helpful MR imaging sequences for a diagnostic algorithm in cases of innumerable brain lesions.

Main Methods:

A retrospective review of 12,495 brain MR imaging studies was conducted.
Studies with 50 or more parenchymal lesions and the term "innumerable" were included.
Patients were categorized into active and chronic groups based on MR and clinical features.

Main Results:

Thirty-one studies met inclusion criteria, with 19 active and 12 chronic processes.
The active group primarily comprised metastasis (9), infarction (6), and microbleeds (2).
Malignancy and immunosuppression were identified as key risk factors.

Conclusions:

Active innumerable brain lesions on MRI occur in 0.25% of studies.
Metastasis and infarction were the most common causes in the active group, identified by specific MRI sequences.
A diagnostic algorithm incorporating MR features and risk factors can guide brain biopsy decisions.