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Precision Pharmacotherapy: Integrating Pharmacogenomics into Clinical Pharmacy Practice
J Kevin Hicks1, Christina L Aquilante1, Henry M Dunnenberger1
1American College of Clinical Pharmacy.
Clinical pharmacogenomics advances precision pharmacotherapy by guiding drug selection and dosing. This paper details real-world applications and recommends how the American College of Clinical Pharmacy can advance its implementation, education, and research.
Area of Science:
- Pharmacology
- Genetics
- Clinical Pharmacy
Background:
- Precision pharmacotherapy integrates patient-specific factors for optimized drug therapy.
- Clinical pharmacogenomics, a rapidly evolving field, is central to personalized medicine.
- Clinical pharmacists are crucial in implementing and advancing pharmacogenomics.
Purpose of the Study:
- To articulate real-world clinical applications of precision pharmacotherapy via clinical pharmacogenomics.
- To provide recommendations for the American College of Clinical Pharmacy (ACCP) to support pharmacogenomics advancement.
- To identify commonalities in successful pharmacogenomics programs for broader implementation.
Main Methods:
- Review of clinical applications of precision pharmacotherapy, focusing on pharmacogenomics.
- Analysis of successful clinical pharmacogenomics implementation and education programs.
- Development of recommendations for ACCP to foster pharmacogenomics practice, education, and research.
Main Results:
- Clinical pharmacogenomics offers practical applications in guiding drug selection and dosing.
- Key commonalities exist in successful pharmacogenomics implementation and education initiatives.
- ACCP can play a vital role in advancing clinical pharmacogenomics through targeted support.
Conclusions:
- Clinical pharmacogenomics is integral to precision pharmacotherapy, with pharmacists leading its integration.
- Strategic support from ACCP is essential for expanding pharmacogenomics education, implementation, and research.
- Further research is needed to fully realize the potential of pharmacogenomics in clinical practice.
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