Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Clinical Applications of Epidermal Stem Cells

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Reinforcement of bio-apatite by zinc substitution in the incisor tooth of a prawn.

Acta biomaterialia·2020

Same author

Growth, Size Rank, and Maturation of the Freshwater Prawn, Macrobrachium rosenbergii: Analysis of Marked Prawns in an Experimental Population.

The Biological bulletin·2018

Same author

Intersex Red Claw Crayfish, Cherax quadricarinatus (von Martens): Functional Males with Pre-vitellogenic Ovaries.

The Biological bulletin·2017

Same author

Effect of Methyl Farnesoate on Late Larval Development and Metamorphosis in the Prawn Macrobrachium rosenbergii (Decapoda, Palaemonidae): A Juvenoid-like Effect?

The Biological bulletin·2017

Same author

Identification and Characterization of an Insulin-Like Receptor Involved in Crustacean Reproduction.

Endocrinology·2015

Same author

Moral development and discipline encounter in delinquent and nondelinquent adolescents.

Journal of youth and adolescence·2013

Search research articles

Related Experiment Video

Updated: Jul 24, 2026

Generation of a Three-dimensional Full Thickness Skin Equivalent and Automated Wounding

Generation of a Three-dimensional Full Thickness Skin Equivalent and Automated Wounding

Published on: February 26, 2015

[Initial clinical experience using Dermodress, a new temporary biological skin substitute].

M Walter, A Sagi, M M Feuchtwanger

Langenbecks Archiv Fur Chirurgie

|January 1, 1987

Summary

Dermodress, a chemically treated bovine skin graft substitute, shows promise for deep burn treatment. It adheres well, stops bleeding, and prevents infection, facilitating timely autografting.

More Related Videos

Generation of Genetically Modified Organotypic Skin Cultures Using Devitalized Human Dermis

Generation of Genetically Modified Organotypic Skin Cultures Using Devitalized Human Dermis

Published on: December 14, 2015

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

Related Experiment Videos

Last Updated: Jul 24, 2026

Generation of a Three-dimensional Full Thickness Skin Equivalent and Automated Wounding

Generation of a Three-dimensional Full Thickness Skin Equivalent and Automated Wounding

Published on: February 26, 2015

Generation of Genetically Modified Organotypic Skin Cultures Using Devitalized Human Dermis

Generation of Genetically Modified Organotypic Skin Cultures Using Devitalized Human Dermis

Published on: December 14, 2015

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

Area of Science:

Biomaterials science
Regenerative medicine
Wound healing

Context:

Deep burn injuries present significant challenges in wound management and require effective skin substitutes.
Current temporary skin substitutes often have limitations in terms of adherence, infection control, and suitability for immediate grafting.

Purpose:

To evaluate the efficacy and properties of Dermodress, a novel chemically treated bovine skin, as a long-term temporary skin substitute for deep burn wounds.

Summary:

Dermodress, a bovine skin-derived biomaterial, was applied to debrided deep burn surfaces and remained for up to 56 days.
The material demonstrated excellent adherence, hemostatic properties, and no signs of infection or rejection.
It allows for staged removal and immediate autografting due to the clean wound bed it creates.

Impact:

Dermodress exhibits key characteristics required for a successful long-term temporary skin substitute.
Its properties may improve outcomes for patients with deep burn injuries by facilitating timely and effective wound closure.