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Aquapheresis: An Institutional Experience.

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Aquapheresis (AQ) effectively removes excess fluid in various conditions beyond heart failure, showing no significant creatinine changes. This simpler extracorporeal therapy offers an alternative to complex hemodialysis.

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Area of Science:

  • Nephrology
  • Cardiology
  • Critical Care Medicine

Background:

  • Aquapheresis (AQ) is an extracorporeal therapy for fluid removal using a semipermeable membrane.
  • It's primarily used for diuretic-resistant heart failure to manage fluid overload.
  • AQ equipment is simpler to operate than traditional dialysis machines.

Purpose of the Study:

  • To retrospectively analyze the diverse clinical indications for Aquapheresis (AQ) use.
  • To evaluate the safety and efficacy of AQ in non-heart failure scenarios.

Main Methods:

  • Retrospective chart review of patients who underwent AQ therapy at Lenox Hill Hospital.
  • Data collected included indications, duration, volume removed, and changes in creatinine levels.
  • Patient records were identified via electronic health record search for 'Aquaph'.

Main Results:

  • Twenty-three patients initiated AQ therapy; mean daily removal was 1954 mL with no significant creatinine change.
  • Primary indications included cardiogenic shock (10), anasarca (5), acute tubular necrosis (ATN) with volume overload (4), end-stage kidney disease (ESKD) (2), and post-operative overload (2).

Conclusions:

  • Aquapheresis (AQ) demonstrates utility in a broader range of clinical conditions than previously established.
  • The therapy's ease of use and simpler equipment present advantages over traditional hemodialysis for fluid management.