Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

8.4K
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
8.4K
Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

14.3K
The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
14.3K
Two-Dimensional Microscopy in Microbiology01:29

Two-Dimensional Microscopy in Microbiology

913
Two-dimensional (2D) microscopy encompasses a range of optical techniques that capture images within a single focal plane, offering detailed representations of microscopic structures. These techniques are essential in biological and medical research, enabling the visualization of cellular and subcellular structures with different levels of contrast and specificity.There are several major types of 2D microscopy, each with strengths and applications.Bright-Field MicroscopyBright-field microscopy...
913
Overview of Electron Microscopy01:25

Overview of Electron Microscopy

12.5K
The wavelengths of visible light ultimately limit the maximum theoretical resolution of images created by light microscopes. Most light microscopes can only magnify 1000X, and a few can magnify up to 1500X. Electrons, like electromagnetic radiation, can behave like waves, but with wavelengths of 0.005 nm, they produce significantly greater resolution up to 0.05 nm as compared to 500 nm for visible light. An electron microscope (EM) can create a sharp image that is magnified up to 2,000,000X.
12.5K
Transmission Electron Microscopy01:15

Transmission Electron Microscopy

6.6K
In 1931, physicist Ernst Ruska—building on the idea that magnetic fields can direct an electron beam just as lenses can direct a beam of light in an optical microscope—developed the first prototype of the electron microscope. This development led to the development of the field of electron microscopy. In the transmission electron microscope (TEM), electrons are produced by a hot tungsten element and accelerated by a potential difference in an electron gun, which gives them up to 400...
6.6K
Three-Dimensional Microscopy in Microbiology01:28

Three-Dimensional Microscopy in Microbiology

654
Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...
654

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Automated laboratory x-ray diffractometer and fluorescence spectrometer for high-throughput materials characterization.

The Review of scientific instruments·2026
Same author

Microstructure regulates early-stage corrosion behavior and systemic aluminum fate in biodegradable Mg-Al alloys: Integrated in-vitro and in-vivo insights.

Acta biomaterialia·2025
Same author

A nanocalorimeter designed for use with high-resolution transmission electron microscopy.

The Review of scientific instruments·2025
Same author

Development of a dual-spectroscopic system to rapidly measure diisopropyl methyl phosphonate (DIMP) decomposition and temperature in a reactive powder environment.

The Review of scientific instruments·2024
Same author

High-throughput quantification of quasistatic, dynamic and spall strength of materials across 10 orders of strain rates.

PNAS nexus·2024
Same author

Incomplete reactions in nanothermite composites.

Journal of applied physics·2024
Same journal

Can nanozymes achieve more than enzymes?

Nature reviews. Materials·2026
Same journal

Delivering living medicines with biomaterials.

Nature reviews. Materials·2026
Same journal

Materials Advances for Distributed Environmental Sensor Networks at Scale.

Nature reviews. Materials·2026
Same journal

Atomically thin bioelectronics.

Nature reviews. Materials·2025
Same journal

Ingestible Electronics for Diagnostics and Therapy.

Nature reviews. Materials·2025
Same journal

Materials and device strategies to enhance spatiotemporal resolution in bioelectronics.

Nature reviews. Materials·2025
See all related articles

Related Experiment Video

Updated: Dec 7, 2025

Characterization of Calcification Events Using Live Optical and Electron Microscopy Techniques in a Marine Tubeworm
15:39

Characterization of Calcification Events Using Live Optical and Electron Microscopy Techniques in a Marine Tubeworm

Published on: February 28, 2017

8.5K

Looking at education through the microscope.

Suhas Eswarappa Prameela1,2, Patricia M McGuiggan1, Amy Brusini3

  • 1Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD USA.

Nature Reviews. Materials
|September 30, 2020
PubMed
Summary
This summary is machine-generated.

Advanced research microscopes offer hands-on STEM education opportunities for students. Initiatives at Johns Hopkins University showcase the benefits of using sophisticated microscopy in undergraduate STEM learning.

Keywords:
EducationImaging techniques

More Related Videos

Visual and Microscopic Evaluation of Streptomyces Developmental Mutants
08:42

Visual and Microscopic Evaluation of Streptomyces Developmental Mutants

Published on: September 12, 2018

18.6K
Setting Up a Simple Light Sheet Microscope for In Toto Imaging of C. elegans Development
08:37

Setting Up a Simple Light Sheet Microscope for In Toto Imaging of C. elegans Development

Published on: May 5, 2014

23.6K

Related Experiment Videos

Last Updated: Dec 7, 2025

Characterization of Calcification Events Using Live Optical and Electron Microscopy Techniques in a Marine Tubeworm
15:39

Characterization of Calcification Events Using Live Optical and Electron Microscopy Techniques in a Marine Tubeworm

Published on: February 28, 2017

8.5K
Visual and Microscopic Evaluation of Streptomyces Developmental Mutants
08:42

Visual and Microscopic Evaluation of Streptomyces Developmental Mutants

Published on: September 12, 2018

18.6K
Setting Up a Simple Light Sheet Microscope for In Toto Imaging of C. elegans Development
08:37

Setting Up a Simple Light Sheet Microscope for In Toto Imaging of C. elegans Development

Published on: May 5, 2014

23.6K

Area of Science:

  • Microscopy
  • STEM Education

Background:

  • Universities possess advanced research microscopes.
  • These instruments are often underutilized in undergraduate education.

Purpose of the Study:

  • To explore the integration of advanced research microscopes into STEM curricula.
  • To demonstrate the educational value of hands-on microscopy experience for students.

Main Methods:

  • Case study of initiatives at Johns Hopkins University.
  • Analysis of student engagement with sophisticated microscopy equipment.

Main Results:

  • Students gained practical skills using advanced microscopes.
  • Hands-on experience enhanced understanding of scientific concepts.

Conclusions:

  • Advanced research microscopes can significantly improve STEM education.
  • Integrating such tools provides valuable experiential learning opportunities for students.