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Severe Necrosis and Cellulitis Complicating Treatment with Interferon β-1a
Chun-Chen Chang1, Chien-Hui Lin2, Jen-Jen Su3
1Department of Neurology, Lee General Hospital.
Purpose:
A case report with a review of the current literature concerning cutaneous necrosis has occasionally been reported in interferon therapy.
Case Report:
We report a 19-year-old woman diagnosed multiple sclerosis for three years. She selfinjected the standard dose of recombinant interferonβ-1a (12 million units) subcutaneously three times a week. Severe necrotizing cutaneous reactions over abdomen Happened and she must receive parental antibiotics and surgical debridement.
Conclusion:
Our observation emphasizes the importance of educating patients on the proper selfadministration of subcutaneous injections of interferon β.
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