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Author Spotlight: Enhancing Rheumatoid Arthritis Research Through HR-pQCT Imaging Analysis
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Non-radiographic axial spondyloarthritis
Hideto Kameda1, Shigeto Kobayashi2, Naoto Tamura3
1Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Toho University, Tokyo, Japan.
Modern Rheumatology
|September 30, 2020
Summary
Non-radiographic axial spondyloarthritis (nr-axSpA) is a distinct form of axial spondyloarthritis. New diagnostic guidelines and targeted therapies, including IL-17 inhibitors, are emerging for nr-axSpA in Japan.
Area of Science:
- Rheumatology
- Immunology
Background:
- Non-radiographic axial spondyloarthritis (nr-axSpA) is a subgroup of axial spondyloarthritis (axSpA).
- nr-axSpA shares features with ankylosing spondylitis (AS) but differs in sex distribution and inflammatory markers.
- Diagnostic criteria and treatment options for nr-axSpA are evolving.
Purpose of the Study:
- To outline recent developments in the diagnosis and treatment of nr-axSpA in Japan.
- To highlight the introduction of new therapeutic agents for nr-axSpA.
Main Methods:
- Review of diagnostic guidance for nr-axSpA in Japan.
- Discussion of the approval and availability of biological agents.
Main Results:
- Diagnostic guidance for nr-axSpA has been proposed in Japan.
- An IL-17 inhibitor was approved for nr-axSpA in August 2020.
- Additional biological agents are expected to become available for Japanese patients.
Conclusions:
- The landscape for managing nr-axSpA in Japan is rapidly advancing.
- Targeted therapies offer new hope for patients with nr-axSpA.
- Future treatment options will expand for Japanese patients with nr-axSpA.
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