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Early Selective C-Reactive Protein Apheresis in a Patient with Acute ST Segment Elevation Myocardial Reinfarction
Maja Milosevic1, Bela Balint1,2, Srdjan Boskovic1,3
1Dedinje Cardiovascular Institute, Belgrade, Serbia.
Insights
A patient experiencing stent thrombosis after stopping antiplatelet medication underwent successful treatment. CRP apheresis was utilized to manage high C-reactive protein levels, leading to an uneventful recovery.
Area of Science:
- Cardiology
- Interventional Cardiology
- Biomedical Engineering
Background:
- Acute stent thrombosis is a serious complication following percutaneous coronary intervention.
- Ticagrelor non-adherence is a significant risk factor for stent thrombosis.
- Elevated C-reactive protein (CRP) levels can indicate ongoing inflammation in cardiovascular events.
Abstract:
The patient was admitted for urgent coronary angiography following an acute anterior ST segment elevation myocardial reinfarction (STEMI) caused by acute stent thrombosis. A stent had been implanted 10 days prior to the reinfarction for an acute anterior STEMI. However, the patient had stopped taking ticagrelor post-discharge. Primary percutaneous coronary intervention of the left anterior descending artery was performed. Subsequently, due to a high C-reactive protein (CRP) level, 3 CRP apheresis sessions were performed, with the first session starting 12 h after the onset of symptoms. A significant drop in CRP was noted after each apheresis. The post-procedural course was uneventful.
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