Related Experiment Video
Updated: Dec 7, 2025
Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management
Published on: January 19, 2024
Effect of Delayed Versus Early Cord Clamping on Improving Anemia in Term Infants Aged Two Months or Older - A
1Department of Neonatology, The First Hospital of Jilin University, Changchun 130021, China.
Objective:
To assess the effects of delayed cord clamping (DCC) on hemoglobin (Hb), mean corpuscular volume (MCV) and ferritin level in infants 2 months or older.
Evidence Acquisition:
Meta-analysis of randomized control trials searched systematically from PubMed, Cochrane and Web of science. Trials published from Jan 1,1975 to Mar 12, 2018, no language and country restrictions. Twelve studies were included in this meta-analysis. In total, 993 infants were treated with DCC, while 989 cases received early cord clamping. Delayed cord clamping was defined as umbilical cord clamping time greater than 60s after delivery. Outcomes assed were (i) hemoglobin (Hb), (ii) mean corpuscular volume (MCV) and ferritin level.
Results:
The results show that DCC increased hemoglobin level (SMD=0.4678 95%CI: [0.1515, 0.7841]), Ferritin level (SMD=2.1450 95%CI: [1.0431, 3.2470]) and MCV (SMD=0.5751 95%CI: [0.1637, 0.9865]) in infants between 2-12 months compared to ECC subject analysis noted the effects of Hb increase was greater in Asian infants.
Conclusions:
Delayed cord clamping improved the Hb, MCV and ferritin level of infants after birth.
More Related Videos
07:36Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
07:26Isolation and Characterization of Human Umbilical Cord-derived Mesenchymal Stem Cells from Preterm and Term Infants
Published on: January 26, 2019