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Bacillus cereus: Epidemiology, Virulence Factors, and Host-Pathogen Interactions

Daniel Enosi Tuipulotu1, Anukriti Mathur1, Chinh Ngo1

  • 1Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia.

Trends in Microbiology
|October 2, 2020
PubMed
Summary

Bacillus cereus toxins, hemolysin BL (HBL) and nonhemolytic enterotoxin (NHE), trigger inflammation and cell death by activating the NLRP3 inflammasome. Understanding these bacterial toxins and host interactions is key to combating food poisoning.

Keywords:
IL-1IL-18S-layerToll-like receptorsanthraxbacteremiacaspase-1cytokinesemesisendophthalmitisendosporesflagellagasdermingasgangrenegastroenteritisgut microbiomegut microbiotamesophilicpsychrotrophicrespiratory tract infections

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