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Related Concept Videos

Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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The Functions of the Skeletal System01:22

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The most apparent functions of the skeletal system are support, protection, and movement. However, bone tissue also performs several other critical metabolic functions. For one, the bone matrix acts as a reservoir for a number of minerals important to the functioning of the body, especially calcium and phosphorus. These minerals, present in the bone tissue, can be released back into the bloodstream when required. Calcium ions, for example, are essential for muscle contractions and controlling...
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Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
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What is the Skeletal System?01:02

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Overview
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Disorders of Hemostasis01:24

Disorders of Hemostasis

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Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
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Blood and Nerve Supply to the Bones01:29

Blood and Nerve Supply to the Bones

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Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
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Relationship between bone disorders and stroke.

Milija D Mijajlovic1, Vuk Aleksic2, Natasa Stojanovski3

  • 1Neurology Clinic, Clinical Center of Serbia, Faculty of Medicine, School of Medicine University of Belgrade, Dr Subotica 6, Belgrade, 11000, Serbia. milijamijajlovic@yahoo.com.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|October 2, 2020
PubMed
Summary
This summary is machine-generated.

Bone disorders rarely cause stroke, but stroke significantly impacts bone health, leading to osteoporosis and fractures. This review explores their complex, bidirectional relationship, highlighting stroke

Keywords:
Bone PathologyBone disordersRisk factorsStroke

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Area of Science:

  • Neurology
  • Orthopedics
  • Metabolic Bone Disease

Background:

  • Bone disorders are infrequent causes of cerebrovascular accidents (stroke).
  • Osteoporosis/osteopenia and increased fracture risk are recognized complications following stroke.
  • A complex, bidirectional relationship exists between stroke and bone health, with shared risk factors.

Purpose of the Study:

  • To review the existing evidence on the intricate connection between bone health and stroke.
  • To address the significant gap in understanding how bone pathology influences cerebrovascular events and vice versa.

Main Methods:

  • Extensive literature review.
  • Synthesis of current evidence on the relationship between bone disorders and stroke.

Main Results:

  • Bone pathology is an uncommon cause of stroke.
  • Stroke has a more pronounced effect on bone health than previously understood.
  • Shared risk factors contribute to both conditions, and they can act as risk factors for each other.

Conclusions:

  • The link between stroke and bone health is complex and warrants further investigation.
  • While bone disorders are rare stroke causes, their impact on post-stroke bone health is significant.
  • Understanding this relationship is crucial for comprehensive patient management.