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Published on: January 10, 2025
Exposure to cough aerosols and development of pulmonary COVID-19
Koen Vanden Driessche1,2, Jeremy Nestele3, Jeroen Grouwels3
1Division of Pulmonology, Department of Pediatrics, University Hospital Antwerp, Wilrijkstraat 10, 2650, Edegem, Belgium.
Abstract:
We hypothesized that most patients with severe pulmonary COVID-19 were exposed to cough aerosols. Among patients that were almost 100% certain which person infected them, only 14 out of 38 overall, and 9 out of 25 hospitalized patients requiring supplemental oxygen, were infected by someone who coughed, which did not support our hypothesis. Talking, especially with a loud voice, could be an alternative source generating SARS-CoV-2 aerosols. Further research is needed to determine how SARS-CoV-2 spreads. Avoiding to talk when you are not wearing your mask and not talking with a loud voice, 'voice etiquette', could be other public health interventions worthwhile exploring.
Insights
Coughing may not be the primary source of severe COVID-19 transmission. Talking loudly could generate infectious SARS-CoV-2 aerosols, suggesting new public health strategies like
Area of Science:
- Respiratory Medicine
- Infectious Diseases
- Public Health
Background:
- Severe COVID-19 transmission dynamics require further investigation.
- Understanding aerosol generation is crucial for effective prevention strategies.
Purpose of the Study:
- To test the hypothesis that cough aerosols are the primary source of severe COVID-19 infection.
- To explore alternative aerosol-generating activities, such as talking, in SARS-CoV-2 transmission.
Main Methods:
- Patient interviews to determine the source of infection.
- Analysis of infection transmission pathways in severe COVID-19 cases.
Main Results:
- A small proportion of patients (14/38 overall, 9/25 hospitalized) identified coughing as the infection source.
- This finding did not support the initial hypothesis regarding cough aerosols.
Conclusions:
- Coughing may not be the sole or primary driver of severe COVID-19 spread.
- Talking, particularly with a loud voice, presents a potential alternative source of SARS-CoV-2 aerosols.
- Further research into SARS-CoV-2 transmission routes is essential.
- Exploring 'voice etiquette' as a public health intervention warrants consideration.
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