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Peripheral facial nerve palsy associated with COVID-19
Marco A Lima1,2, Marcus Tulius T Silva3,4, Cristiane N Soares5
1Laboratory of Clinical Research in Neuroinfections (LAPCLIN-NEURO), Evandro Chagas National Institute of Infectious Diseases (INI), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil. marco.lima@ini.fiocruz.br.
Journal of Neurovirology
|October 2, 2020
Summary
Peripheral facial palsy, a neurological symptom, can occur during COVID-19 infection. This study details eight cases, finding steroids effective for recovery, suggesting it
Area of Science:
- Neurology
- Infectious Diseases
- Virology
Background:
- The COVID-19 pandemic has been associated with diverse neurological complications.
- Peripheral facial palsy (Bell's palsy) is a recognized neurological condition affecting facial nerves.
Purpose of the Study:
- To investigate the clinical, laboratory, and radiological characteristics of peripheral facial palsy in COVID-19 patients.
- To assess the outcomes and treatment responses in these patients.
Main Methods:
- Retrospective case series describing eight patients with COVID-19 and peripheral facial palsy.
- Clinical assessment of facial nerve dysfunction (mild/moderate).
- Cerebrospinal fluid (CSF) analysis via PCR for SARS-CoV-2.
Main Results:
- Eight COVID-19 patients developed peripheral facial palsy; for three, it was the initial symptom.
- Facial nerve damage ranged from mild to moderate dysfunction.
- SARS-CoV-2 was not detected in CSF samples.
- Seven patients received steroid treatment, with all showing complete or partial symptom recovery.
Conclusions:
- Peripheral facial palsy is a potential neurological manifestation of COVID-19.
- Steroid therapy appears effective in managing COVID-19-associated facial palsy.
- This condition should be recognized as part of the neurological spectrum of SARS-CoV-2 infection.
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