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Respiratory, growth, and survival outcomes of infants with tracheostomy and ventilator dependence
Gangaram Akangire1,2, Jane B Taylor3, Susan McAnany4
1Division of Neonatology, Children's Mercy Kansas City, Kansas City, MO, USA. gakangire@cmh.edu.
Insights
Outcomes for infants with tracheostomy are not well documented. This study found that premature infants with tracheostomy showed improved survival and earlier decannulation, with consistent growth patterns.
Area of Science:
- Pediatric Pulmonology
- Neonatology
- Pediatric Critical Care
Background:
- Outcomes for infants requiring tracheostomy are not well described in existing literature.
- There is a need to better understand respiratory, growth, and survival trajectories in this population.
Purpose of the Study:
- To describe the respiratory, growth, and survival outcomes of infants with tracheostomy.
- To compare outcomes between preterm and term infants with tracheostomy.
Main Methods:
- Retrospective study of 204 infants with tracheostomy at <1 year of age.
- Follow-up data collected up to 4 years of age in a multidisciplinary clinic.
Main Results:
- Mean age at tracheostomy was 4.5 months; median decannulation age was 32 months.
- Mortality rate was 21%; preterm infants (<28 weeks gestation) with bronchopulmonary dysplasia (BPD) had higher survival.
- Weight and weight-for-length z-scores improved post-discharge and remained consistent through 3 years.
Conclusions:
- Infants with tracheostomy managed in a multidisciplinary clinic showed improved survival, growth, and earlier decannulation.
- Preterm infants with BPD and tracheostomy had better survival rates than term infants.
- This data is crucial for family counseling and medical staff education.
Background:
Outcome of infants with tracheostomy have not been well described in the literature. Our objective was to describe the respiratory, growth, and survival outcomes of infants with tracheostomy.
Methods:
A retrospective study was conducted on 204 infants born between 2005 and 2015 with tracheostomy at <1 year of age and follow-up in the Infant Tracheostomy and Home Ventilator Clinic up to 4 years of age.
Results:
The mean age at tracheostomy was 4.5 months with median age of 3 months. Median age of decannulation was 32 months. The time from tracheostomy placement to complete discontinuation of mechanical ventilation was 15.4 months and from tracheostomy to decannulation was 33.8 months. Mortality rate was 21% and median age of death was 18 months. Preterm infants with acquired airway and lung disease (BPD) and born at <28 weeks' gestation had a significantly higher survival rate compared to term infants. The z-scores for weight and weight for length improved from the time of discharge (mean chronological age 6.5 months) to first year and remained consistent through 3 years.
Conclusions:
Premature infants had a higher rate of discontinuation of mechanical ventilation and decannulation compared to term infants. These infants showed consistent growth and comparable survival rate.
Impact:
Infants with tracheostomy and ventilator dependence followed in a multidisciplinary clinic model may have improved survival, growth, and earlier time to decannulation. Preterm infants with acquired airway and lung disease (BPD) with tracheostomy had a higher survival rate compared to term infants with various tracheostomy indications. The age at tracheostomy in infants was 4.5 months and of decannulation was 37 months. Time from tracheostomy to complete discontinuation of mechanical ventilation was 15.4 months. Addition of this data to the sparse literature will be crucial in counseling the families and education of medical staff.
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