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Predictive Nomogram for the Necessity of Tracheotomy During Oral and Oropharyngeal Cancer Surgery
Siyuan Xu1, Kai Wang1, Kan Liu2
1Department of Head and Neck Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
Objectives/Hypothesis:
The individualized risk of airway obstruction after head and neck cancer surgery is unclear, especially oral and oropharyngeal cancer. The study aimed to establish an individualized predictive model for the necessity of temporary tracheotomy in these patients.
Methods:
Patients who underwent oral and oropharyngeal cancer surgery from 1999 to 2019 were retrospectively reviewed. A nomogram was developed and validated in patients treated from 1999 to 2009 and 2010 to 2019, respectively.
Results:
In total, 1551 patients were included. Oropharyngeal cancer, large tumor, midline crossing, preoperative radiation, mandibulectomy, flap reconstruction, and neck dissection were independent risk factors of postoperative airway obstruction in the training group (n = 707). A nomogram incorporating these factors had a C-index of 0.931 and was validated in the testing group (n = 844) (C-index, 0.918). Good calibration curves were observed in both groups.
Conclusions:
The nomogram successfully predicted the individual risk of postoperative airway obstruction for patients with oral and oropharyngeal cancer.
Level Of Evidence:
4. Laryngoscope, 131:E1489-E1495, 2021.
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