Related Experiment Video

Updated: Dec 6, 2025

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

15.8K

Comparing laboratory and in-the-wild data for continuous Parkinson's Disease tremor detection

Ada Zhang, Fernando De la Torre, Jessica Hodgins

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |October 6, 2020
    PubMed

    Abstract:

    Passive, continuous monitoring of Parkinson's Disease (PD) symptoms in the wild (i.e., in home environments) could improve disease management, thereby improving a patient's quality of life. We envision a system that uses machine learning to automatically detect PD symptoms from accelerometer data collected in the wild. Building such systems, however, is challenging because it is difficult to obtain labels of symptom occurrences in the wild. Many researchers therefore train machine learning algorithms on laboratory data with the assumption that findings will translate to the wild. This paper assesses how well laboratory data represents wild data by comparing PD symptom (tremor) detection performance of three models on both lab and wild data. Findings indicate that, for this application, laboratory data is not a good representation of wild data. Results also show that training on wild data, even though labels are less precise, leads to better performance on wild data than training on accurate labels from laboratory data.

    More Related Videos

    Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson's Disease
    04:08

    Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson's Disease

    Published on: January 18, 2021

    3.2K
    Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson's Disease Model
    05:38

    Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson's Disease Model

    Published on: January 7, 2019

    18.7K

    Related Experiment Videos

    Last Updated: Dec 6, 2025

    Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
    10:28

    Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

    Published on: July 24, 2019

    15.8K
    Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson's Disease
    04:08

    Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson's Disease

    Published on: January 18, 2021

    3.2K
    Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson's Disease Model
    05:38

    Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson's Disease Model

    Published on: January 7, 2019

    18.7K

    Related Concept Videos

    Parkinson's Disease: Overview01:15

    Parkinson's Disease: Overview

    1.5K
    Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
    1.5K
    Parkinson's Disease: Treatment01:24

    Parkinson's Disease: Treatment

    802
    Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
    Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
    802

    Articles linked to this work by shared authors, journal, and citation graph.

    ZEST: Zero-shot embodied skill transfer for athletic robot control.

    Science robotics·2026

    Honey Bees Reduce Pollen Viability While Foraging.

    Insects·2026

    A public mid-density genotyping platform for cultivated cranberry (Vaccinium macrocarpon Aiton).

    The plant genome·2025

    Integration across biophysical scales identifies molecular and cellular correlates of person-to-person variability in human brain connectivity.

    Nature neuroscience·2024

    Properties and Functional Analysis of Two Chorismate Mutases from Maritime Pine.

    Cells·2024

    Intersectional Hybrids between Darrow's Blueberry (V. darrowii Camp) and Lingonberry (V. vitis-idaea L.).

    Plants (Basel, Switzerland)·2024

    Analysis of End-Tidal CO2 Variability During Plateau Waves Episodes: An Information Theoretic Approach.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    AI and Tomosynthesis for Breast Cancer Molecular Subtyping: A step toward precision medicine.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    Towards Sustainable Protein Recovery from Biological Waste: Assessing Polyethersulfone-based Microfiltration.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    Analysis of the cardiovascular response to standardized polymicrobial peritonitis experimental model.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    Automated Wrist Ultrasound Image Bone Enhancement and Segmentation Using Deep Learning.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    A Deep Learning approach for Depressive Symptoms assessment in Parkinson's disease patients using facial videos.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    Clinical EEG In Modern Psychiatry: Diagnostics and Prediction.

    Clinical EEG and neuroscience·2026

    Bell's Palsy in 11,255 Cases: Cardiometabolic Associations in a Population-Based Healthcare Database.

    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us