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Extralobar pulmonary sequestration with elevated serum neuron-specific enolase: A case report and review of the
Feng-Wei Kong1, Wei-Min Wang1, Longbo Gong2
1Department of General Surgery, Xuzhou Infectious Disease Hospital.
Rationale:
Pulmonary sequestration (PS) presenting with elevated serum tumor markers is rare, and it might be misdiagnosed as malignancy.
Patient Concerns:
A 26-year-old asymptomatic male patient was admitted because the x-ray showed an intrathoracic lesion. Meanwhile, the serum neuron-specific enolase (NSE) was elevated. Three-dimensional computed tomography angiography revealed an isolated feeding vessel arising from the aorta.
Diagnoses:
Extralobular PS was confirmed by computed tomography angiography and postoperative pathological staining.
Interventions:
Two-port thoracoscopic resection of the sequestrated lobe was performed.
Outcomes:
The serum NSE decreased to within the normal range and persisted during the follow up of 10 months.
Lessons:
A thorough work-up should be considered for the PS patients presenting with abnormal serum NSE. Detailed knowledge regarding the relationship between NSE and PS necessitates further studies.
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