Is the Stability of a Standard Stable Reference Stable Enough?

The dogmatic approach of following the past principles has made many significant features of science go unnoticed and unquestioned. One such is the concept of immutability of the anterior contour of the sella turcica. For many decades, we have been using the anterior contour of sella turcica as a stable reference structure to study the growth of the craniofacial skeleton.¹ This was based on the usage by Björk and Skieller. But on analyzing the various studies on the growth and disease of the pituitary gland and its influence on the size and morphology of sella turcica, it seems that the anterior contour of the sella turcica may not be a stable parameter of reference. This article is an attempt to throw light on the intricacies of the association between pituitary gland and sella turcica.