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Updated: Dec 6, 2025

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
Optical Coherence Tomography Angiography for Evaluation of Retinal Vascular Changes in Patients with Psoriasis
Abdurrahman Alpaslan Alkan1, Ceylan Uslu Doğan2, İbrahim Çağrı Türker2
1Department of Ophthalmology, Erciş Şehit Rıdvan Çevik State Hospital, Van, Turkey.
Objectives:
To investigate foveal avascular zone (FAZ) area and retinal vascular density (VD) in patients with psoriasis according to disease severity using optical coherence tomography angiography (OCTA).
Methods:
Twenty-seven patients with mild psoriasis (Group 1), 28 with moderate to severe psoriasis (Group 2) and 30 healthy controls (Group 3) were evaluated with OCTA. Foveal and parafoveal VD and FAZ area were measured and compared.
Results:
FAZ values were significantly higher in Group 2 (0.20 ± 0.1, 0.31 ± 0.07, 0.20 ± 0.09; P < .001, respectively.). The mean VD value were significantly lower in the deep capillary plexus in parafoveal area in Group 2 (35.5 ± 8.7, 28.7 ± 4.6, 35.0 ± 3.5; P < .001, respectively.). These changes showed significant correlation with Psoriasis Area and Severity Index (PASI) scores of patients.
Conclusions:
Our results suggest that OCTA may have a future role as alert of potentially more severe disease in cases clinically classified as mild disease.
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