Related Experiment Video

Updated: Dec 6, 2025

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
11:20

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

4.1K

Endophthalmitis Caused by Abiotrophia Defectiva after Anterior Vitrectomy in a Child

Helio V Neves da Silva1, Anna Mackin1, Jesse Smith1

  • 1Department of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado, USA.

Ocular Immunology and Inflammation
|October 6, 2020
PubMed

Insights

This is the first reported case of endophthalmitis caused by Abiotrophia defectiva in a child. Advanced diagnostic methods like 16S rDNA PCR and MALDI-TOF will increase detection of this rare infection.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Endophthalmitis is a serious intraocular infection.
  • Abiotrophia defectiva is a rare cause of endophthalmitis, with no prior pediatric cases reported.

Observation:

  • A 12-year-old female developed endophthalmitis following penetrating keratoplasty, open globe injury repair, and anterior vitrectomy.
  • The causative agent was identified as Abiotrophia defectiva.

Findings:

  • This case represents the first documented instance of Abiotrophia defectiva-induced endophthalmitis in a pediatric patient.
  • Review of existing literature on Abiotrophia defectiva endophthalmitis was conducted.

Implications:

  • The study highlights the importance of considering Abiotrophia defectiva in pediatric endophthalmitis cases.
  • Increased utilization of 16S rDNA PCR and MALDI-TOF mass spectrometry is expected to improve the diagnosis of Abiotrophia defectiva infections.

Keywords:
Abiotrophia defectivaEndophthalmitisNutrient Variant Streptococci

More Related Videos

Iris Fixation via External Pentagram Suturing05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

1.6K
Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy11:03

Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy

Published on: January 22, 2018

10.4K

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.1K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
987
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
861