Overactive Bladder Symptoms in Patients with Fibromyalgia: A Systematic Case-Controlled Study

Area of Science:

• Urology
• Rheumatology
• Clinical Research

Background:

• A prior survey suggested a connection between fibromyalgia and overactive bladder (OAB).
• This study aimed to systematically investigate this association.

Purpose of the Study:

• To conduct the first systematic case-controlled study comparing OAB symptoms in fibromyalgia patients versus matched controls.
• To assess the prevalence and severity of OAB symptoms in individuals with fibromyalgia.

Main Methods:

• A case-controlled study involving 27 fibromyalgia patients and 26 healthy controls.
• Participants completed the Overactive Bladder Symptom Score (OAB-q8) and Revised Fibromyalgia Impact Questionnaire (FIQR).
• Groups were matched for age, sex, and ethnicity, with exclusion criteria for relevant medications, infections, or prior surgeries.

Main Results:

• A significantly higher prevalence of OAB was observed in fibromyalgia patients (93%) compared to controls (19%) (p < 0.001).
• Fibromyalgia patients reported more severe OAB symptoms, with higher mean OAB-q8 scores (24.4 vs. 10.8, p < 0.001).
• A positive correlation was found between OAB symptom severity and fibromyalgia impact (rs = 0.727, p < 0.001).

Conclusions:

• This study confirms a significant association between fibromyalgia and overactive bladder symptoms.
• The high prevalence of OAB in fibromyalgia patients underscores its importance as a urological comorbidity.
• Routine assessment of OAB symptoms is recommended for individuals diagnosed with fibromyalgia.