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Updated: Dec 6, 2025
Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates
Published on: January 27, 2019
Case Report: COVID-19 and Chagas Disease in Two Coinfected Patients
Ricardo Wesley Alberca1, Tatiana Mina Yendo1, Yasmim Álefe Leuzzi Ramos1
11Departamento de Dermatologia, Faculdade de Medicina FMUSP, Laboratorio de Dermatologia e Imunodeficiencias (LIM-56), Universidade de Sao Paulo, Sao Paulo, Brazil.
Insights
This study reports the first cases of coinfection with Chagas disease (CD) and COVID-19. Both patients diagnosed with Trypanosoma cruzi and SARS-CoV-2 infection unfortunately died.
Area of Science:
- Infectious Diseases
- Parasitology
- Virology
Background:
- Chagas disease (CD), caused by Trypanosoma cruzi, is a significant global health concern.
- COVID-19, caused by SARS-CoV-2, is known to cause lymphopenia and mortality.
- Coinfection with these two distinct pathogens presents a unique clinical challenge.
Abstract:
American trypanosomiasis, also named Chagas disease (CD), is an anthropozoonosis caused by the protozoan parasite Trypanosoma cruzi. The disease affects millions of people worldwide, leading yearly to approximately 50,000 deaths. COVID-19, generated by SARS-CoV-2, can lead to lymphopenia and death. We hereby describe the first report of two patients with CD and COVID-19 coinfection, from hospitalization until patients' death.
