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Updated: Dec 6, 2025

Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research
Published on: October 13, 2023
[Sjögren Syndrome : the ENT specialist contributes to the workup]
Alexandra Breitenstein1, Laure Brülhart2, Yves Jaquet3
1Service d'ORL et chirurgie cervico-faciale, HUG, 1211 Genève 14, et Réseau hospitalier neuchâtelois, Rue de la Maladière 45, 2000 Neuchâtel.
Abstract:
Sjögren Syndrome is an autoimmune disorder presenting as Sicca syndrome (dry-eye, dry mouth) and most often multiorgan involvement with various clinical manifestations. The diagnostic criteria defined by the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR) include biologic, histologic parameters and functional measurements. Part of this workup can be performed by the ENT specialist. It encompasses minor salivary gland biopsy, sialometry, Schirmer lacrymal test and major salivary gland ultrasound. These tests and their performances are described. The growing importance of major salivary gland ultrasound as a follow-up and diagnostic tool is also discussed in this article.
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