1,2-Migrations onto Gold Carbene Centers
Tao Wang1, A Stephen K Hashmi2,3
1Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, No. 620 West Chang'an Avenue, Xi'an 710119, China.
Abstract:
Gold carbenes are highly active intermediates in homogeneous gold catalysis, enabling a large array of transformations such as C-H/X-H insertions, cyclopropanations, and 1,2-migrations. Unlike C-H/X-H insertions and cyclopropanations, 1,2-migrations onto gold carbene centers seem to be attracting less attention. There has been no comprehensive review focusing on this topic, even though this chemistry has become a powerful tool for the rapid and simple construction of molecular complexity. This review provides comprehensive and critical information on the 1,2-migrations onto gold carbene centers, drawing a preliminary conclusion on the migratory aptitude of various groups. The review is divided into several parts according to the kind of carbene precursors.
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