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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Glaucoma: Overview01:25

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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How Does Cataract Surgery Rate Affect Angle-closure Prevalence.

Guangming Jin1, Lanhua Wang1, Jane Scheetz2

  • 1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, People's Republic of China.

Journal of Glaucoma
|October 8, 2020
PubMed
Summary
This summary is machine-generated.

Increasing cataract surgery rates, particularly for individuals over 70, can significantly reduce the prevalence of occludable angles, a precursor to angle-closure glaucoma.

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Area of Science:

  • Ophthalmology
  • Public Health
  • Glaucoma Research

Background:

  • Primary angle-closure glaucoma (PACG) poses a significant public health challenge, particularly in Asian populations.
  • Occludable angle (OA) is a key risk factor for PACG.
  • Cataract surgery rates (CSR) may influence the prevalence of OA.

Purpose of the Study:

  • To estimate the effect of varying cataract surgical rates (CSR) on the prevalence of primary angle-closure glaucoma (PACG) in the Chinese population.
  • To investigate the relationship between CSR and occludable angle (OA) prevalence.

Main Methods:

  • A simulation study using data from the Liwan Eye Study (participants aged 50+).
  • Occludable angle (OA) prevalence was evaluated using gonioscopy, and anterior chamber depth measured via ultrasound.
  • Logistic function models predicted OA prevalence across simulated CSRs.

Main Results:

  • Projected OA prevalence decreased as CSR increased.
  • A notable decrease in OA rates was observed with rising CSR in individuals aged 70 years and older.
  • The study simulated OA prevalence across CSRs ranging from 2000 to 12,000.

Conclusions:

  • Increased CSR is associated with a reduced prevalence of occludable angles, especially in older populations.
  • Timely cataract surgery for individuals in their late 60s to 70s with significant cataracts is advisable to mitigate PACG risk.
  • This suggests a potential public health strategy for PACG prevention through enhanced cataract surgery interventions.