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Updated: Dec 6, 2025

Characterization of Leukocyte-platelet Rich Fibrin, A Novel Biomaterial
Published on: September 29, 2015
[The use of platelet rich plasma in bone-reconstructive in cranio-maxillo-facial surgery]
V I Ermolin1, M A Mokhirev1, E M Romanova1
1National Medical Research Center of Dentistry and Maxillofacial Surgery of Ministry of Health of the Russian Federation, Moscow, Russia.
Abstract:
PRP-therapy - method, based on local application platelet rich plasma. Efficiency of this method is investigated and approved both in vitro and in vivo. PRP includes growth factors: platelet derived growth factor, transforming growth factor, epidermal growth factor, insulin-like growth factor, vascular endothelial growth factor, which significantly accelerate regenerative process. PRP-therapy reduces pain syndrome, accelerates tissue regeneration and has an anti-inflammatory effect.

