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Related Experiment Video

Updated: Dec 6, 2025

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
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Sacral neuromodulation system for treating refractory overactive bladder.

Alice Phillips1

  • 1Urology Specialist Nurse, Salford Royal NHS Foundation Trust.

British Journal of Nursing (Mark Allen Publishing)
|October 9, 2020
PubMed
Summary

Sacral neuromodulation (SNM) offers a safe solution for overactive bladder (OAB) by modulating nerve activity. New guidance highlights the Axonics SNM System, a rechargeable option potentially offering cost benefits and improved patient choice.

Keywords:
NICE guidanceOveractive bladder (OAB)Sacral neuromodulation (SNM)

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Area of Science:

  • Urology
  • Neurology
  • Medical Devices

Background:

  • Overactive bladder (OAB) affects quality of life and can be treated with sacral neuromodulation (SNM).
  • SNM involves electrical stimulation of sacral nerves to normalize bladder-brain communication.
  • For refractory OAB cases unresponsive to conservative treatments, minimally invasive SNM is an option.

Purpose of the Study:

  • To review the Axonics SNM System for treating refractory OAB, as per recent NICE guidance.
  • To highlight the benefits of rechargeable SNM systems, including longevity and reduced need for revision surgery.
  • To discuss the impact of multiple SNM therapy options on patient choice and care.

Main Methods:

  • Review of National Institute for Health and Care Excellence (NICE) guidance on the Axonics SNM System.
  • Analysis of SNM therapy principles and its application in managing overactive bladder.
  • Inclusion of three case studies demonstrating practical application of the Axonics system.

Main Results:

  • The Axonics SNM System is a rechargeable device with a longevity of at least 15 years.
  • NICE guidance suggests potential cost advantages for the NHS with the Axonics System.
  • Availability of multiple SNM systems, including rechargeable options, expands patient choices.

Conclusions:

  • Sacral neuromodulation is a safe and effective therapy for improving bladder function in OAB patients.
  • The Axonics SNM System offers a long-lasting, rechargeable solution, potentially providing cost-effectiveness.
  • Increased availability of SNM technologies enhances therapeutic options and patient-centered care for OAB.