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Updated: Dec 6, 2025

Exploiting Live Imaging to Track Nuclei During Myoblast Differentiation and Fusion
Published on: April 13, 2019
Colocalization of tracks from boron neutron capture reactions and images of isolated cells
Ian Postuma1, Patrizia Sommi2, Agostina Vitali3
1Istituto Nazionale di Fisica Nucleare sez, di Pavia, Via Agostino Bassi 6, Pavia, 27100, Italy.
Abstract:
In Boron Neutron Capture Therapy, the boronated drug plays a leading role in delivering a lethal dose to the tumour. The effectiveness depends on the boron macroscopic concentration and on its distribution at sub-cellular level. This work shows a way to colocalize alpha particles and lithium ions tracks with cells. A neutron autoradiography technique is used, which combines images of cells with images of tracks produced in a solid-state nuclear track detector.
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