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Novel coronavirus disease in patients with end-stage kidney disease

Noriaki Shimada1, Hiroaki Shimada2, Yoshiaki Itaya1

  • 1Medical Corporation JISEIKAI Tachibana Clinic, Tokyo, Japan.

Therapeutic Apheresis and Dialysis : Official Peer-Reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy
|October 11, 2020
PubMed

Insights

Patients with end-stage kidney disease on hemodialysis face a higher risk of novel coronavirus disease (COVID-19) infection and mortality. Rapid implementation of preventive measures in dialysis facilities is crucial to mitigate spread.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Public Health

Background:

  • The COVID-19 pandemic, originating in Wuhan, China, poses a significant threat globally.
  • End-stage kidney disease patients undergoing hemodialysis (HD) are a vulnerable population with increased infection risk.
  • Comorbidities common in renal failure, like hypertension and cardiovascular disease, exacerbate COVID-19 severity and mortality.

Purpose of the Study:

  • To review the latest findings on COVID-19 in patients with end-stage kidney disease.
  • To summarize current global guidelines for preventing COVID-19 spread in dialysis facilities.

Main Methods:

  • Literature review of recent studies on COVID-19 in end-stage kidney disease patients.
  • Compilation and analysis of international guidelines for infection control in dialysis settings.

Main Results:

  • Dialysis patients exhibit significantly higher morbidity and mortality rates from COVID-19 compared to the general population.
  • No specific treatments for COVID-19 are currently available, emphasizing the need for prevention.

Conclusions:

  • Urgent establishment of effective countermeasures in dialysis facilities is essential to protect this high-risk group.
  • Proactive infection control strategies are critical for managing COVID-19 in end-stage kidney disease patients undergoing HD.

Keywords:
COVID-19infection controlkidney failurerenal dialysis

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