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Related Experiment Video

Updated: Dec 6, 2025

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Movement Disorders and Renal Diseases.

Suvorit S Bhowmick1, Anthony E Lang1

  • 1Division of Neurology, Department of Medicine, Morton and Gloria Shulman Movement Disorders Clinic and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital University Health Network Toronto Ontario Canada.

Movement Disorders Clinical Practice
|October 12, 2020
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Summary

This review highlights disorders where movement abnormalities and kidney dysfunction stem from shared pathophysiological processes, not direct causation. Early recognition aids diagnosis and management of these complex neurological and renal conditions.

Keywords:
movement disordersnephropathyneurogenetics.

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Area of Science:

  • Nephrology
  • Neurology
  • Genetics

Background:

  • Movement disorders and kidney disease frequently coexist.
  • These conditions can arise from direct causation or shared underlying pathologies.
  • Understanding these links is crucial for comprehensive patient care.

Purpose of the Study:

  • To review inherited and acquired disorders linking nervous system and kidney pathophysiology.
  • To increase neurologist awareness of these specific conditions.
  • To improve early identification and management of patients with both movement and renal issues.

Main Methods:

  • Literature review focusing on disorders with common pathophysiological mechanisms.
  • Analysis of the interplay between neurological and renal systems.
  • Synthesis of current understanding of associated conditions.

Main Results:

  • Identified several inherited and acquired disorders where movement abnormalities and renal dysfunction share common pathophysiological roots.
  • Highlighted that these conditions are distinct from direct cause-and-effect relationships.
  • Emphasized the importance of recognizing these overlaps for diagnosis.

Conclusions:

  • Increased awareness among neurologists can lead to earlier detection of renal involvement.
  • Anticipating complications and targeting shared mechanisms improve patient outcomes.
  • Diagnosing renal impairment aids in narrowing differential diagnoses for complex neurological presentations.