Four new triterpene glucosides from Salacia cochinchinensis Lour

Four new triterpene glucosides (1-4) were isolated from the 90% ethanol extract of Salacia cochinchinensis, together with five known compounds (5-9). The structures of the new compounds were elucidated by comprehensive spectroscopic analysis including HRESIMS, IR, 1 D and 2 D NMR analysis. All isolates were assayed for their α-glucosidase inhibitory activity. Compound 9 showed remarkable α-glucosidase inhibitory activity with an IC₅₀ value of 0.31 μM, and the triterpene glycosides (1-5) exhibited moderate α-glucosidase inhibitory activity.