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Updated: Dec 6, 2025

One-pot Microwave-assisted Conversion of Anomeric Nitrate-esters to Trichloroacetimidates
Published on: January 15, 2018
Co-Catalyzed Transannulation of Pyridotriazoles with Isothiocyanates and Xanthate Esters
Ziyan Zhang1, Vladimir Gevorgyan1
1Department of Chemistry and Biochemistry, University of Texas at Dallas, 800 W. Campbell Road, Richardson, Texas 75080, United States.
Abstract:
An efficient radical transannulation reaction of pyridotriazoles with isothiocyanates and xanthate esters was developed. This method features conversion of pyridotriazoles into two N-fused heterocyclic aromatic systems-imino-thiazolopyridines and oxo-thiazolopyridine derivatives-via one-step Co(II)-catalyzed transannulation reaction proceeding via a radical mechanism. The synthetic usefulness of the developed method was illustrated in the synthesis of amino acid derivatives and further transformations of obtained reaction products.
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