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Using Optical Quality Analysis System for predicting surgical parameters in age-related cataract patients
Thibaud Garcin1,2, Damien Grivet1, Gilles Thuret1,2,3
1Ophthalmology Department, University Hospital, Saint-Etienne, France.
Plos One
|October 12, 2020
Summary
The Optical Quality Analysis System (OQAS) objectively measures cataract impact on vision. OQAS parameters correlate with clinical grading and surgical needs, offering objective assessment for improved cataract surgery planning.
Area of Science:
- Ophthalmology
- Biomedical Optics
- Medical Imaging
Background:
- Age-related cataract significantly impairs vision and necessitates surgical intervention.
- Current clinical grading of lens opacity, such as the Lens Opacity Classification System III (LOCS III), has limitations in objective quantification.
- Objective optical quality measurements are needed to complement subjective clinical assessments.
Purpose of the Study:
- To evaluate the contribution of the Optical Quality Analysis System (OQAS) in assessing age-related cataract.
- To determine the relationships between OQAS parameters, clinical grading (LOCS III), and cataract surgery phacodynamics (CDE, US time).
- To explore the potential of OQAS for objective cataract grading and surgical planning.
Main Methods:
- A monocentric clinical study involving 21 patients (76±8 years) with various cataract types (nuclear, cortical, mixed).
- OQAS measurements included Objective Scatter Index (OSI), Modulation Transfer Function (MTF), and Strehl Ratio (SR).
- Clinical grading used LOCS III and best-corrected visual acuity (BCVA). Phacodynamics parameters included cumulative dissipated energy (CDE) and ultrasound time (US time).
Main Results:
- OQAS parameters (OSI, MTF, SR) significantly correlated with BCVA and LOCS III grading.
- OSI showed strong correlation with cortical cataract components, while MTF correlated with nuclear components.
- OSI demonstrated strong correlations with phacodynamics parameters (CDE and US time), particularly for cortical cataracts.
Conclusions:
- OQAS provides objective and complementary measurements for cataract grading, correlating well with clinical assessments and surgical parameters.
- OSI is valuable for assessing the optical impact of cortical cataracts, and MTF for nuclear cataracts.
- OQAS holds potential for optimizing surgical parameters, such as energy distribution in femtosecond laser-assisted cataract surgery.
