Related Experiment Video

Updated: Dec 6, 2025

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training
07:40

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training

Published on: October 10, 2019

7.6K

Cardiac Troponin Testing in Patients with COVID-19: A Strategy for Testing and Reporting Results

Peter A Kavsak1, Ola Hammarsten2, Andrew Worster1

  • 1McMaster University, Hamilton, Ontario, Canada.

Clinical Chemistry
|October 12, 2020
PubMed

Insights

Cardiac troponin is a key prognostic indicator for COVID-19 patients, but its interpretation and role require further study. This review examines SARS-CoV-2

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Biomarkers

Background:

  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can impact the cardiovascular system.
  • Elevated cardiac troponin levels are recognized as a significant prognostic marker in hospitalized COVID-19 patients.
  • Early pandemic literature revealed considerable uncertainty regarding the reporting, interpretation, and underlying pathophysiology of increased cardiac troponin in COVID-19.

Purpose of the Study:

  • To review the pathophysiology of SARS-CoV-2 and its effects on the cardiovascular system.
  • To critically evaluate the strengths and limitations of studies assessing cardiac troponin in COVID-19 patients.
  • To propose recommended cardiac troponin testing strategies for different phases of COVID-19 illness and recovery.

Main Methods:

  • Literature review of studies on SARS-CoV-2, cardiovascular effects, and cardiac troponin.
  • Analysis of existing research to identify trends, inconsistencies, and knowledge gaps.
  • Synthesis of findings to develop evidence-based recommendations for clinical practice.

Main Results:

  • The review highlights the established link between SARS-CoV-2 infection and cardiovascular complications.
  • It identifies variability in study methodologies and reporting standards for cardiac troponin assays.
  • Gaps in understanding the precise mechanisms and clinical utility of troponin elevation in COVID-19 are noted.

Conclusions:

  • Cardiac troponin plays a crucial role in prognostication for COVID-19 patients.
  • Further well-designed research is essential to clarify the role and optimize testing strategies for cardiac troponin in COVID-19.
  • Standardized approaches to troponin testing are needed for consistent patient management.
Abstract

Keywords:
COVID-19acute carecardiac troponinrisk stratification

More Related Videos

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

24.6K
Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease06:16

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease

Published on: August 9, 2024

698

Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
117
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
631
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
451
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
128
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
163
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
93