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Multimodal chiropractic care for migraine: A pilot randomized controlled trial.
Pamela M Rist1, Carolyn Bernstein2,3, Matthew Kowalski3
1Division of Preventive Medicine, Department of Medicine, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.
Cephalalgia : an International Journal of Headache
|October 14, 2020
Summary
Multimodal chiropractic care plus enhanced usual care (MCC+) may reduce migraine days more than enhanced usual care alone. This pilot study suggests MCC+ warrants further investigation for episodic migraine management.
Area of Science:
- Neurology
- Integrative Medicine
- Clinical Trials
Background:
- Spinal manipulation shows potential for reducing migraine frequency.
- However, the efficacy of multimodal chiropractic care for migraines remains unevaluated.
Purpose of the Study:
- To assess the feasibility and safety of multimodal chiropractic care plus enhanced usual care (MCC+) in adult women with episodic migraine.
- To explore the preliminary effects of MCC+ on migraine frequency.
Main Methods:
- A pilot randomized controlled trial compared MCC+ to enhanced usual care (EUC) alone.
- Participants received 10 chiropractic sessions over 14 weeks or usual medical care and education.
- Feasibility outcomes included recruitment, retention, adherence, and safety; migraine days were a secondary outcome.
Main Results:
- Sixty-one women were randomized; high adherence and follow-up rates were observed.
- Multimodal chiropractic care participants reported a greater reduction in migraine days (-2.9 days) compared to the EUC group (-1.0 days).
- No serious adverse events were reported, though non-serious events were more frequent in the MCC+ group.
Conclusions:
- While pre-specified feasibility criteria were not fully met, the study demonstrated potential for multimodal chiropractic care in migraine management.
- Preliminary findings support conducting a definitive trial to further evaluate MCC+ for episodic migraine.
