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[Cardio-oncology: At the crossroads between two fields].

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Updated: Dec 6, 2025

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[Tumor effects on the heart and circulation].

M S Anker1,2,3,4, S Hadzibegovic5,6,7,8, S von Haehling9,10

  • 1Medizinische Klinik für Kardiologie, Charité - Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Deutschland. markus.anker@charite.de.

Der Internist
|October 14, 2020
PubMed
Summary

Cardio-oncology addresses heart problems in cancer patients due to treatments like chemotherapy and cancer itself. Early detection of cardiovascular risks is crucial for better patient outcomes and mobility.

Keywords:
CardiotoxicityCardiovascular diseasesHeart rate variabilityResting heart rateTumour

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Area of Science:

  • Oncology and Cardiology
  • Cardio-oncology

Background:

  • Modern cancer treatments improve survival but can cause cardiotoxicity.
  • Cardiovascular issues are common before, during, and after cancer therapy.
  • Cancer itself can negatively impact the heart via specific mechanisms.

Purpose of the Study:

  • To highlight the growing importance of cardio-oncology.
  • To underscore the challenges posed by cardiovascular comorbidities in cancer patients.
  • To emphasize the need for identifying cancer patients at high cardiovascular risk.

Main Methods:

  • Review of cardiotoxic effects from various cancer therapies (chemotherapy, immunotherapy, etc.).
  • Examination of cardiovascular complications, including heart failure and valve damage.
  • Exploration of direct cardiac effects of tumors and associated molecular mediators.

Main Results:

  • Cancer therapies pose significant risks of cardiotoxicity.
  • Undetected cardiotoxicity can lead to severe cardiac conditions.
  • Tumors can directly harm the cardiovascular system.

Conclusions:

  • Cardio-oncology is essential for managing cancer treatment side effects.
  • Understanding cardiovascular risks in cancer patients is key.
  • Developing targeted therapeutic approaches can improve prognosis and maintain patient mobility.