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Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
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Categorising a problem: alcohol and dementia.
Gabriele Cipriani1,2, Angelo Nuti3, Cecilia Carlesi3
1Neurology Unit, Versilia Hospital, Lido di Camaiore, Camaiore, Italy. cprgrl@gmail.com.
Acta Neurologica Belgica
|October 14, 2020
Summary
Chronic alcohol consumption can cause brain damage and cognitive deficits. This review examines the complex relationship between alcohol use disorders and dementia, exploring its causes and prevalence.
Area of Science:
- Neuroscience
- Neurology
- Public Health
Background:
- Alcoholism is a chronic relapsing disorder with significant neurological consequences.
- Long-term ethanol exposure is known to cause brain damage in humans.
- The link between alcohol consumption and dementia is a growing public health concern.
Purpose of the Study:
- To review the existing literature on the relationship between alcohol use and dementia.
- To explore the contributing factors, pathogenesis, and prevalence of alcohol-related dementia.
Main Methods:
- Comprehensive literature search of Medline and Google Scholar databases up to 2019.
- Inclusion of relevant articles, chapters, and books using keywords such as 'alcohol consumption,' 'alcohol-related dementia,' and 'dementia.'
- Review of identified publications and their references for further relevant information.
Main Results:
- Alcohol affects the central nervous system through direct and indirect mechanisms.
- There is a consensus that alcohol use contributes to cognitive deficits in later life.
- Debate continues regarding the exact causes, classification, and prevalence of alcohol-related dementia.
Conclusions:
- Alcohol consumption is a significant factor in the development of cognitive impairments and dementia.
- Further research is needed to clarify the specific mechanisms and diagnostic criteria for alcohol-related dementia.
- Understanding the dose-response relationship between alcohol intake and dementia risk is crucial for prevention strategies.
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