Cardioembolic Stroke: Risk Factors, Clinical Features, and Early Outcome in 956 Consecutive Patients

Kilian Griñán1, Adrià Arboix1, Joan Massons1

  • 1Cerebrovascular Division, Department of Neurology, Hospital Universitari Sagrat Cor, Barcelona, Spain.

Insights

Identifying predictors like atrial fibrillation and ischemic heart disease is crucial for early cardioembolic stroke classification. This helps improve patient management and outcomes.

Area of Science:

  • Neurology
  • Cardiology
  • Stroke Medicine

Background:

  • Limited data exists on early clinical features of cardioembolic stroke before diagnostic imaging.
  • Understanding these early signs is vital for timely intervention.

Purpose of the Study:

  • To identify risk factors, clinical features, and early outcomes of cardioembolic stroke.
  • To differentiate cardioembolic stroke from atherothrombotic stroke based on early indicators.

Main Methods:

  • Retrospective analysis of prospectively collected data from a hospital-based stroke registry.
  • Comparison of patients with cardioembolic infarction versus atherothrombotic stroke.
  • Multivariate logistic regression to assess predictors of cardioembolic infarction.

Main Results:

  • Atrial fibrillation (AF), ischemic heart disease, female gender, and sudden onset were significant predictors of cardioembolic stroke.
  • Advanced age (≥85 years) and congestive heart failure were more frequent in the cardioembolic group.
  • Hypertension, diabetes, and smoking were more prevalent in the atherothrombotic group.

Conclusions:

  • Early identification of cardioembolic stroke through clinical predictors is essential.
  • Comprehensive evaluation is necessary for effective management of potential cardioembolic stroke.
Abstract

Related Concept Videos

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
143
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
315
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
167
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
2.5K
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
236
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
111